The Project Quit team is currently conducting a half–dozen research studies aimed at both…Read More
Female smokers experienced more stress and craving…Read More
The Charleston Animal Society is partnering with M.U.S.C,…Read More
There are approximately 50 million people in America…Read More
New article/feature with Charleston Animal Society…Read More
New article/featured in Lowcountry Dog Magazine on page 10…Read More
Translational Neuropsychopharmacology Research of Nicotine Addiction
Drs. Brett Froeliger and Kevin Gray
This study is investigating the effects of combining 2 medications, Varenicline (commonly known as Chantix®) and N-acetylcysteine, on smoking behavior in daily cigarette smokers who are interested in quitting smoking. The study consists of 10 visits over 6 weeks. Smokers must be between the ages of 18 and 55.
Personalized Smoking Relapse Prevention Delivered in Real-Time via Just-in-Time-Adaptive Interventions: Integrated Tobacco Retail Outlet Location
The QuitBuddy Study
Dr. Bryan Heckman
The purpose of this study is to explore whether “QuitBuddy”, a quit-smoking app, can improve quit attempt outcomes for those using over-the-counter quit medicine by providing reminders and prompts for the most effective times to take a dose. Participants will also use the app to complete surveys about their smoking use and behaviors outside of the clinic visits. Nicotine replacement therapy (lozenges) will be provided at no cost to assist with the quit attempt as well as ongoing study participation. The study involves 6 visits over the course of 3 months.
Mobile, remote, and individual-focused: Comparing breath carbon monoxide readings and abstinence in next generation monitors
Dr. Erin McClure
Current smokers and nonsmokers are needed for an observational study that is comparing carbon monoxide (CO) monitors. CO monitors are used in smoking research to assess smoking use/behavior by assessing the level of carbon monoxide in a breath sample. The study involves almost daily but brief visits over the course of 2 weeks. There is a total of 10 visits after completing the initial screening visit. No quit attempt is required for smokers.
Effects of filter ventilation on sensory response, smoking, topography and inhalation
Dr. Brett Froeliger
Current cigarette smokers that are not looking to actively make a quit attempt within 30 days are needed for an observational/nontreatment study to examine how ventilation levels in cigarette filters influences the appeal of the product as well as risk perceptions and the intent to purchase. This study is completed in 2 visits and will involve smoking various cigarettes and completing surveys and questionnaires.
An fMRI pilot study of the effects of Clavulanic Acid on cigarette withdrawal
Dr. Brett Froeliger
This non-treatment study is looking at the effects of Clavulanic Acid (a drug used in antibiotics) on brain activity with smoking withdrawal. Participants do not need to be looking to quit but must be willing to make a quit attempt during their participation. This study involves 6 visits to the clinic over 2 weeks.
Impact of e-cigarette characteristics on reinforcement and tobacco use patterns among current smokers
K01 E-cig Study
Dr. Tracy Smith
The purpose of this project is to understand how different e-cigarettes influence their likeability and use among current smokers who try using e-cigarettes. Participants will receive an e-cigarette to sample over a three-week period. During this time, they will complete daily electronic diaries and weekly lab visits.
Clinical Outcomes of a Nationwide, Naturalistic E-Cig Trial
Dr. Matthew Carpenter
The purpose of this study is to measure changes in smoking behavior during and following sampling of an e-cigarette product. We are testing the effects of one specific e-cigarette (NJoy) on smoking behavior. Neither the tobacco industry nor any e-cigarette manufacturer provides support of any kind to this study. There is no requirement to quit smoking in this study. This study involves 7 phone calls and 4 study visits over 6 months of participation.
Evaluating transcranial magnetic stimulation as a tool to reduce smoking directly following a quit attempt
Dr. Colleen Hanlon
In this study we are evaluating a new tool to assist individuals with quitting cigarette smoking. Transcranial magnetic stimulation (TMS) is a non-invasive technique that uses magnetic pulses to temporarily stimulate specific brain areas (without the need for surgery, anesthetic, or other invasive procedures). This treatment study will test whether 10 daily sessions of TMS over the forehead can help decrease smoking rates in treatment-seeking individuals. There are a total of 15 study visits completed over 6-8 weeks of participation.
Enhancing self-regulation by altering memories that increase risk of relapse among smokers: A translational clinical neuroscience study of a novel medication
Dr. Michael Saladin
This study is looking to recruit smokers over the age of 18 that are willing to complete a mandatory 2-day abstinence from smoking. Participants will receive either Rapamycin (also known as Sirolimus, an FDA approved drug for use with transplants) or a placebo to assess potential effects on smoking craving and relapse. This study involves 4 visits over the course of about 3 weeks.
Targeting Foundational Memory Processes in Nicotine Addiction: A Translational Clinical Neuroscience Study of a Retrieval-Extinction
Behavioral Memory Modulation in Nicotine Addiction (BMM Study)
Dr. Michael Saladin
This study examines the use of smoking cues (pictures, videos and objects) to change a person’s interest in smoking. This treatment study does NOT involve the use of study medication. Participants will complete 12 clinic visits over the course of 6 months. Participants must be between 22-65 in order to participate.